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Induction of pyroptosis in colon cancer cells by LXRβ
Liver X receptors (LXRs) have been proposed to have some anticancer properties. We recently identified a new non-genomic role of LXRβ in colon cancer cells. Under LXR agonist treatment, LXRβ induces pyroptosis of these cells in vitro and in vivo, raising the possibility of targeting this isoform in...
Autores principales: | Rébé, Cédric, Derangère, Valentin, Ghiringhelli, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905240/ https://www.ncbi.nlm.nih.gov/pubmed/27308405 http://dx.doi.org/10.4161/23723548.2014.970094 |
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