Cargando…
Stop relaxing: How DNA damage-induced chromatin compaction may affect epigenetic integrity and disease
DNA damage is widely recognized for its potential to impair epigenetic integrity. Epigenetic defects are closely associated with a variety of diseases. We have recently uncovered DNA double-strand break-induced chromatin condensation as a critical modulator of repair outcome. Here, we discuss the po...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905243/ https://www.ncbi.nlm.nih.gov/pubmed/27308388 http://dx.doi.org/10.4161/23723548.2014.970952 |