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Two roads to death – Bax targets mitochondria by distinct routes before or during apoptotic cell death

Recent studies have revolutionized our understanding of how the crucial apoptosis effectors Bax and Bak target mitochondria to kill cells. We recently reported that an important determinant of the localization, oligomerization, and apoptotic function of Bax is an interaction with either mitochondria...

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Detalles Bibliográficos
Autor principal: Dewson, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905248/
https://www.ncbi.nlm.nih.gov/pubmed/27308408
http://dx.doi.org/10.4161/23723556.2014.974460