UCP2 induces metabolic reprogramming to inhibit proliferation of cancer cells

Invalidation of uncoupling protein 2 (Ucp2) increases glucose utilization and proliferation in normal cells. We recently reported that cancer cells that overexpress UCP2 become less tumorigenic while switching their metabolism from glycolysis to oxidative phosphorylation. UCP2 appears to be a key re...

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Detalles Bibliográficos
Autores principales: Esteves, Pauline, Pecqueur, Claire, Alves-Guerra, Marie-Clotilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905249/
https://www.ncbi.nlm.nih.gov/pubmed/27308391
http://dx.doi.org/10.4161/23723556.2014.975024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905249/
https://www.ncbi.nlm.nih.gov/pubmed/27308391
http://dx.doi.org/10.4161/23723556.2014.975024

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