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Comparative lineage tracing reveals cellular preferences for prostate cancer initiation

The interplay of different cell types of origin and distinct oncogenic mutations may determine the tumor subtype. We have recently found that although both basal and luminal epithelial cells can initiate prostate tumorigenesis, the latter are more likely to undergo transformation in response to a ra...

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Detalles Bibliográficos
Autores principales: Wang, Zhu A, Shen, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905298/
https://www.ncbi.nlm.nih.gov/pubmed/27308462
http://dx.doi.org/10.4161/23723556.2014.985548