Comparative lineage tracing reveals cellular preferences for prostate cancer initiation

The interplay of different cell types of origin and distinct oncogenic mutations may determine the tumor subtype. We have recently found that although both basal and luminal epithelial cells can initiate prostate tumorigenesis, the latter are more likely to undergo transformation in response to a ra...

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Detalles Bibliográficos
Autores principales: Wang, Zhu A, Shen, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905298/
https://www.ncbi.nlm.nih.gov/pubmed/27308462
http://dx.doi.org/10.4161/23723556.2014.985548
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author Wang, Zhu A
Shen, Michael M
author_facet Wang, Zhu A
Shen, Michael M
author_sort Wang, Zhu A
collection PubMed
description The interplay of different cell types of origin and distinct oncogenic mutations may determine the tumor subtype. We have recently found that although both basal and luminal epithelial cells can initiate prostate tumorigenesis, the latter are more likely to undergo transformation in response to a range of oncogenic events.
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spelling pubmed-49052982016-06-15 Comparative lineage tracing reveals cellular preferences for prostate cancer initiation Wang, Zhu A Shen, Michael M Mol Cell Oncol Author's Views The interplay of different cell types of origin and distinct oncogenic mutations may determine the tumor subtype. We have recently found that although both basal and luminal epithelial cells can initiate prostate tumorigenesis, the latter are more likely to undergo transformation in response to a range of oncogenic events. Taylor & Francis 2015-02-25 /pmc/articles/PMC4905298/ /pubmed/27308462 http://dx.doi.org/10.4161/23723556.2014.985548 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's Views
Wang, Zhu A
Shen, Michael M
Comparative lineage tracing reveals cellular preferences for prostate cancer initiation
title Comparative lineage tracing reveals cellular preferences for prostate cancer initiation
title_full Comparative lineage tracing reveals cellular preferences for prostate cancer initiation
title_fullStr Comparative lineage tracing reveals cellular preferences for prostate cancer initiation
title_full_unstemmed Comparative lineage tracing reveals cellular preferences for prostate cancer initiation
title_short Comparative lineage tracing reveals cellular preferences for prostate cancer initiation
title_sort comparative lineage tracing reveals cellular preferences for prostate cancer initiation
topic Author's Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905298/
https://www.ncbi.nlm.nih.gov/pubmed/27308462
http://dx.doi.org/10.4161/23723556.2014.985548
work_keys_str_mv AT wangzhua comparativelineagetracingrevealscellularpreferencesforprostatecancerinitiation
AT shenmichaelm comparativelineagetracingrevealscellularpreferencesforprostatecancerinitiation

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