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Analysis of intratumor heterogeneity unravels lung cancer evolution

Lung cancer is a disease with dismal outcome. We recently reported a detailed intratumor heterogeneity analysis in 7 non-small cell lung cancer samples, revealing spatially separated driver events as well as the temporal dynamics of mutational processes and demonstrating an important role for APOBEC...

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Detalles Bibliográficos
Autores principales: de Bruin, Elza C, McGranahan, Nicholas, Swanton, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905299/
https://www.ncbi.nlm.nih.gov/pubmed/27308463
http://dx.doi.org/10.4161/23723556.2014.985549