AEG-1–AKT2: A novel complex controlling the aggressiveness of glioblastoma

Expression of AEG-1 (also known as MTDH or LYRIC) is elevated in many cancers including glioblastoma multiforme (GBM), in which it functions as an oncogene. AEG-1 activates AKT signaling and physically interacts with AKT2 in GBM. Disruption of this interaction reduces glioma cell survival and invasi...

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Detalles Bibliográficos
Autores principales: Emdad, Luni, Hu, Bin, Das, Swadesh K, Sarkar, Devanand, Fisher, Paul B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905313/
https://www.ncbi.nlm.nih.gov/pubmed/27308476
http://dx.doi.org/10.4161/23723556.2014.995008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905313/
https://www.ncbi.nlm.nih.gov/pubmed/27308476
http://dx.doi.org/10.4161/23723556.2014.995008

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