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Glutathione peroxidase 4 (Gpx4) and ferroptosis: what's so special about it?
The system X(C)(−)/glutathione/glutathione peroxidase 4 (Gpx4) axis pivotally controls ferroptosis, a recently described form of regulated non-apoptotic cell death. Compelling evidence has established that this route of cell death is not only of high relevance for triggering cancer cell death, but a...
Autores principales: | Conrad, Marcus, Friedmann Angeli, José Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905320/ https://www.ncbi.nlm.nih.gov/pubmed/27308484 http://dx.doi.org/10.4161/23723556.2014.995047 |
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