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The life history of neochromosomes revealed

Neochromosomes are a little-studied class of chromosome-scale mutations that drive some cancers. By sequencing isolated neochromosomes from liposarcomas, we recently defined their structure at single-nucleotide resolution and proposed a model for their life history. Here, we summarize that work, hig...

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Detalles Bibliográficos
Autores principales: Papenfuss, Anthony T, Thomas, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905327/
https://www.ncbi.nlm.nih.gov/pubmed/27308490
http://dx.doi.org/10.1080/23723556.2014.1000698