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Untargeted metabolomics for profiling oncogene-specific metabolic signatures of prostate cancer

Oncogene-associated metabolic signatures in prostate cancer, identified by an integrative analysis of cultured cells and murine and human tumors, suggest that AKT activation results in a glycolytic phenotype whereas MYC induces aberrant lipid metabolism. Heterogeneity in human tumors makes this simp...

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Detalles Bibliográficos
Autores principales: Priolo, Carmen, Loda, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905328/
https://www.ncbi.nlm.nih.gov/pubmed/27308491
http://dx.doi.org/10.1080/23723556.2014.1001197