Trial Watch: Targeting ATM–CHK2 and ATR–CHK1 pathways for anticancer therapy

The ataxia telangiectasia mutated serine/threonine kinase (ATM)/checkpoint kinase 2 (CHEK2, best known as CHK2) and the ATM and Rad3-related serine/threonine kinase (ATR)/CHEK1 (best known as CHK1) cascades are the 2 major signaling pathways driving the DNA damage response (DDR), a network of proces...

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Detalles Bibliográficos
Autores principales: Manic, Gwenola, Obrist, Florine, Sistigu, Antonella, Vitale, Ilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905354/
https://www.ncbi.nlm.nih.gov/pubmed/27308506
http://dx.doi.org/10.1080/23723556.2015.1012976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905354/
https://www.ncbi.nlm.nih.gov/pubmed/27308506
http://dx.doi.org/10.1080/23723556.2015.1012976

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