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Unraveling the therapeutic potential of the LncRNA-dependent noncanonical Hedgehog pathway in cancer

Acquired resistance to Hedgehog pathway inhibitors has been reported in the clinical setting and upregulation of noncanonical Hedgehog signaling is one of the major underlying mechanisms behind this resistance. As demonstrated in our recent study, greater clinical efficacy might be achieved by focus...

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Detalles Bibliográficos
Autores principales: Xing, Zhen, Lin, Chunru, Yang, Liuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905365/
https://www.ncbi.nlm.nih.gov/pubmed/27308519
http://dx.doi.org/10.1080/23723556.2014.998900