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Unraveling the therapeutic potential of the LncRNA-dependent noncanonical Hedgehog pathway in cancer
Acquired resistance to Hedgehog pathway inhibitors has been reported in the clinical setting and upregulation of noncanonical Hedgehog signaling is one of the major underlying mechanisms behind this resistance. As demonstrated in our recent study, greater clinical efficacy might be achieved by focus...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905365/ https://www.ncbi.nlm.nih.gov/pubmed/27308519 http://dx.doi.org/10.1080/23723556.2014.998900 |