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HIF-1 suppresses lipid catabolism to promote cancer progression
Hypoxia-inducible factor 1 (HIF-1) promotes glycolysis in cancer cells, hence sustaining survival. We recently reported that HIF-1 suppresses fatty acid β-oxidation in malignant cells through medium- and long-chain acyl-CoA dehydrogenases. This promotes tumor progression by controlling the level of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905416/ https://www.ncbi.nlm.nih.gov/pubmed/27308514 http://dx.doi.org/10.4161/23723556.2014.980184 |