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Melanoma metastases caught in the AKT

Dysregulated protein kinase B alpha (PKB/AKT1) signaling has been increasingly implicated in melanoma metastasis to distant organs, especially the brain. In a recent study, we expressed activated AKT1 in a non-metastatic melanoma model in vivo and discovered that AKT1 activation decreased tumor late...

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Detalles Bibliográficos
Autores principales: Kircher, David A., Arave, Rowan A., Cho, Joseph H., Holmen, Sheri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905423/
https://www.ncbi.nlm.nih.gov/pubmed/27308635
http://dx.doi.org/10.1080/23723556.2015.1128516