DNA methylation in PRDM8 is indicative for dyskeratosis congenita

Dyskeratosis congenita (DKC) is associated with impaired telomere maintenance and with clinical features of premature aging. In this study, we analysed global DNA methylation (DNAm) profiles of DKC patients. Age-associated DNAm changes were not generally accelerated in DKC, but there were significan...

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Detalles Bibliográficos
Autores principales: Weidner, Carola I., Lin, Qiong, Birkhofer, Carina, Gerstenmaier, Uwe, Kaifie, Andrea, Kirschner, Martin, Bruns, Heiko, Balabanov, Stefan, Trummer, Arne, Stockklausner, Clemens, Höchsmann, Britta, Schrezenmeier, Hubert, Wlodarski, Marcin, Panse, Jens, Brümmendorf, Tim H., Beier, Fabian, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905437/
https://www.ncbi.nlm.nih.gov/pubmed/26909595
http://dx.doi.org/10.18632/oncotarget.7458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905437/
https://www.ncbi.nlm.nih.gov/pubmed/26909595
http://dx.doi.org/10.18632/oncotarget.7458

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