Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling

It is suggested that oxLDL is decisive in the initiation and development of atherosclerotic injuries. The up-regulation of oxidative stress and the generation of ROS act as key modulators in developing pro-atherosclerotic and anti-atherosclerotic processes in the human endothelial wall. In this pres...

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Detalles Bibliográficos
Autores principales: Hung, Ching-Hsia, Chan, Shih-Hung, Chu, Pei-Ming, Lin, Huei-Chen, Tsai, Kun-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905438/
https://www.ncbi.nlm.nih.gov/pubmed/26885898
http://dx.doi.org/10.18632/oncotarget.7387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905438/
https://www.ncbi.nlm.nih.gov/pubmed/26885898
http://dx.doi.org/10.18632/oncotarget.7387

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