Immunogenicity and safety of xenogeneic vascular endothelial growth factor receptor-2 DNA vaccination in mice and dogs

Vascular endothelial growth factor receptor-2 (VEGFR-2) is an attractive target in oncology due to its crucial role in angiogenesis. In this study a DNA vaccine coding for human VEGFR-2 was evaluated in healthy mice and dogs, administered by intradermal injection and electroporation. In mice, three...

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Detalles Bibliográficos
Autores principales: Denies, Sofie, Cicchelero, Laetitia, Polis, Ingeborgh, Sanders, Niek N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905448/
https://www.ncbi.nlm.nih.gov/pubmed/26871296
http://dx.doi.org/10.18632/oncotarget.7265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905448/
https://www.ncbi.nlm.nih.gov/pubmed/26871296
http://dx.doi.org/10.18632/oncotarget.7265

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