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Immunogenicity and safety of xenogeneic vascular endothelial growth factor receptor-2 DNA vaccination in mice and dogs

Vascular endothelial growth factor receptor-2 (VEGFR-2) is an attractive target in oncology due to its crucial role in angiogenesis. In this study a DNA vaccine coding for human VEGFR-2 was evaluated in healthy mice and dogs, administered by intradermal injection and electroporation. In mice, three...

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Detalles Bibliográficos
Autores principales:	Denies, Sofie, Cicchelero, Laetitia, Polis, Ingeborgh, Sanders, Niek N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905448/ https://www.ncbi.nlm.nih.gov/pubmed/26871296 http://dx.doi.org/10.18632/oncotarget.7265

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