Compensatory roles of CD8(+) T cells and plasmacytoid dendritic cells in gut immune regulation for reduced function of CD4(+) Tregs

CD4(+) Tregs need to migrate from the mucosal periphery into the draining lymph node via CCR7 to exert their suppressive effects. In this study, we investigated whether CCR7 deficiency resulted in failure of immune suppression in 2% dextran sulfate sodium-induced colitis. Unexpectedly, intestinal in...

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Detalles Bibliográficos
Autores principales: Kim, Young-In, Lee, Bo-Ra, Cheon, Jae-Hee, Kwon, Bo-Eun, Kweon, Mi-Na, Ko, Hyun-Jeong, Chang, Sun-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905450/
https://www.ncbi.nlm.nih.gov/pubmed/26908454
http://dx.doi.org/10.18632/oncotarget.7510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905450/
https://www.ncbi.nlm.nih.gov/pubmed/26908454
http://dx.doi.org/10.18632/oncotarget.7510

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