Gain-of-function miRNA signature by mutant p53 associates with poor cancer outcome

Missense mutation of p53 not only impairs its tumor suppression function, but also causes oncogenic gain of function (GOF). The molecular underpinning of mutant p53 (mutp53) GOF is not fully understood, especially for the potential roles of non-coding genes. Here we identify the microRNA expression...

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Detalles Bibliográficos
Autores principales: Zhang, Yao, Hu, Ye, Fang, Jing-Yuan, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905457/
https://www.ncbi.nlm.nih.gov/pubmed/26840456
http://dx.doi.org/10.18632/oncotarget.7090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905457/
https://www.ncbi.nlm.nih.gov/pubmed/26840456
http://dx.doi.org/10.18632/oncotarget.7090

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