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Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration

The oncogenic role of microRNA-155 (miR-155) in leukemia is well established but its role in other cancers, especially breast cancer, is gradually emerging. In this study we examined the effect of mir-155 loss in a well-characterized spontaneous breast cancer mouse model where Brca1 and Trp53 are de...

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Detalles Bibliográficos
Autores principales: Kim, Sinae, Song, Jin Hoi, Kim, Seokho, Qu, Peng, Martin, Betty K., Sehareen, Waheed S., Haines, Diana C., Lin, Pengnian C., Sharan, Shyam K., Chang, Suhwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905460/
https://www.ncbi.nlm.nih.gov/pubmed/26848978
http://dx.doi.org/10.18632/oncotarget.7150