Cargando…
Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration
The oncogenic role of microRNA-155 (miR-155) in leukemia is well established but its role in other cancers, especially breast cancer, is gradually emerging. In this study we examined the effect of mir-155 loss in a well-characterized spontaneous breast cancer mouse model where Brca1 and Trp53 are de...
Autores principales: | Kim, Sinae, Song, Jin Hoi, Kim, Seokho, Qu, Peng, Martin, Betty K., Sehareen, Waheed S., Haines, Diana C., Lin, Pengnian C., Sharan, Shyam K., Chang, Suhwan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905460/ https://www.ncbi.nlm.nih.gov/pubmed/26848978 http://dx.doi.org/10.18632/oncotarget.7150 |
Ejemplares similares
-
Epigenetic control of an oncogenic microRNA, miR-155, by BRCA1
por: Chang, Suhwan, et al.
Publicado: (2012) -
Targeting YAP-dependent MDSC infiltration impairs tumor progression
por: Wang, Guocan, et al.
Publicado: (2015) -
C/EBP-δ positively regulates MDSC expansion and endothelial VEGFR2 expression in tumor development
por: Min, Yongfen, et al.
Publicado: (2017) -
Suppressing MDSC Infiltration in Tumor Microenvironment Serves as an Option for Treating Ovarian Cancer Metastasis
por: Li, Yichen, et al.
Publicado: (2022) -
microRNA-155 positively regulates glucose metabolism via PIK3R1-FOXO3a-cMYC axis in breast cancer
por: Kim, Sinae, et al.
Publicado: (2018)