Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression

The global methylation profile and the mutational status of 633 specific epigenetic regulators were analyzed in the pediatric tumor clear cell sarcoma of the kidney (CCSK). Methylation array analyses of 30 CCSKs revealed CCSK tumor DNA to be globally hypermethylated compared to Wilms tumor, normal f...

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Detalles Bibliográficos
Autores principales: Karlsson, Jenny, Valind, Anders, Jansson, Caroline, O'Sullivan, Maureen J., Mengelbier, Linda Holmquist, Gisselsson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905462/
https://www.ncbi.nlm.nih.gov/pubmed/26848979
http://dx.doi.org/10.18632/oncotarget.7152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905462/
https://www.ncbi.nlm.nih.gov/pubmed/26848979
http://dx.doi.org/10.18632/oncotarget.7152

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