Mucin glycosylating enzyme GALNT2 suppresses malignancy in gastric adenocarcinoma by reducing MET phosphorylation

Glycosylation affects malignancy in cancer. Here, we report that N- acetylgalactosaminyltransferase 2 (GALNT2), an enzyme that mediates the initial step of mucin type-O glycosylation, suppresses malignant phenotypes in gastric adenocarcinoma (GCA) by modifying MET (Hepatocyte growth factor receptor)...

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Detalles Bibliográficos
Autores principales: Liu, Shin-Yun, Shun, Chia-Tung, Hung, Kuan-Yu, Juan, Hsueh-Fen, Hsu, Chia-Lang, Huang, Min-Chuan, Lai, I-Rue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905470/
https://www.ncbi.nlm.nih.gov/pubmed/26848976
http://dx.doi.org/10.18632/oncotarget.7081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905470/
https://www.ncbi.nlm.nih.gov/pubmed/26848976
http://dx.doi.org/10.18632/oncotarget.7081

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