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Identification of quinazoline compounds as novel potent inhibitors of Wnt/β-catenin signaling in colorectal cancer cells
The Wnt/β-catenin signaling pathway is critical for the initiation and progression of most colon cancers, and has emerged as one of the most promising targets for colorectal cancer chemoprevention and treatment. In this study, we have discovered a structurally related series of quinazolines as poten...
Autores principales: | Li, Yonghe, Lu, Wenyan, Saini, Surendra K., Moukha-Chafiq, Omar, Pathak, Vibha, Ananthan, Subramaniam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905471/ https://www.ncbi.nlm.nih.gov/pubmed/26820295 http://dx.doi.org/10.18632/oncotarget.7019 |
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