Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells

Bone dissemination and bone disease occur in approximately 80% of patients with multiple myeloma (MM) and are a major cause of patient mortality. We previously demonstrated that MM cell-derived heparanase (HPSE) is a major driver of MM dissemination to and progression in new bone sites. However the...

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Detalles Bibliográficos
Autores principales: Li, Juan, Pan, Qianying, Rowan, Patrick D., Trotter, Timothy N., Peker, Deniz, Regal, Kellie M., Javed, Amjad, Suva, Larry J., Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905474/
https://www.ncbi.nlm.nih.gov/pubmed/26849235
http://dx.doi.org/10.18632/oncotarget.7170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905474/
https://www.ncbi.nlm.nih.gov/pubmed/26849235
http://dx.doi.org/10.18632/oncotarget.7170

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