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Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity

Raf kinase inhibitory protein (RKIP) functions as a chemo-immunotherapeutic sensitizer of cancers, but regulation of RKIP on tumor radiosensitivity remains largely unexplored. In this study, we investigate the role and mechanism of RKIP in nasopharyngeal carcinoma (NPC) radioresistance. The results...

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Detalles Bibliográficos
Autores principales: Yuan, Li, Yi, Hong-Mei, Yi, Hong, Qu, Jia-Quan, Zhu, Jin-Feng, Li, Li-Na, Xiao, Ta, Zheng, Zhen, Lu, Shan-Shan, Xiao, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905486/
https://www.ncbi.nlm.nih.gov/pubmed/26862850
http://dx.doi.org/10.18632/oncotarget.7201