Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy

Resistance to human epidermal growth factor receptor 2 (HER2)-targeted therapies in the treatment of HER2-positive breast cancer is a major clinical problem. To identify pathways linked to resistance, we generated HER2-positive breast cancer cell lines which are resistant to either lapatinib or AZD8...

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Detalles Bibliográficos
Autores principales: Creedon, Helen, Gómez-Cuadrado, Laura, Tarnauskaitė, Žygimantė, Balla, Jozef, Canel, Marta, MacLeod, Kenneth G., Serrels, Bryan, Fraser, Craig, Unciti-Broceta, Asier, Tracey, Natasha, Le Bihan, Thierry, Klinowska, Teresa, Sims, Andrew H., Byron, Adam, Brunton, Valerie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905492/
https://www.ncbi.nlm.nih.gov/pubmed/26883193
http://dx.doi.org/10.18632/oncotarget.7317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905492/
https://www.ncbi.nlm.nih.gov/pubmed/26883193
http://dx.doi.org/10.18632/oncotarget.7317

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