Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-κB pathway

The NF-κB pathway is overexpressed in non-small cell lung cancers (NSCLC) and contributes to the poor prognosis and high mortality characterizing this malignancy. Silencing the p50 and p65 NF-κB subunits in the NSCLC H1299 cell line led to profound loss in cell viability and downregulated anti-apopt...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, Si Han Sherman, Ali, Azhar, Chin, Tan Min, Go, Mei Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905498/
https://www.ncbi.nlm.nih.gov/pubmed/26872379
http://dx.doi.org/10.18632/oncotarget.7299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905498/
https://www.ncbi.nlm.nih.gov/pubmed/26872379
http://dx.doi.org/10.18632/oncotarget.7299

Ejemplares similares