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Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling

Chemo/radio-therapy resistance to the deadly pancreatic cancer is mainly due to the failure to kill pancreatic cancer stem cells (CSCs). Signal transducer and activator of transcription 3 (STAT3) is activated in pancreatic CSCs and, therefore, may be a valid target for overcoming therapeutic resista...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoqing, Tang, Wenhua, Marquez, Rebecca T., Li, Ke, Highfill, Chad A., He, Fengtian, Lian, Jiqin, Lin, Jiayuh, Fuchs, James R., Ji, Min, Li, Ling, Xu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905505/
https://www.ncbi.nlm.nih.gov/pubmed/26887043
http://dx.doi.org/10.18632/oncotarget.7336