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Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling
Chemo/radio-therapy resistance to the deadly pancreatic cancer is mainly due to the failure to kill pancreatic cancer stem cells (CSCs). Signal transducer and activator of transcription 3 (STAT3) is activated in pancreatic CSCs and, therefore, may be a valid target for overcoming therapeutic resista...
Autores principales: | Wu, Xiaoqing, Tang, Wenhua, Marquez, Rebecca T., Li, Ke, Highfill, Chad A., He, Fengtian, Lian, Jiqin, Lin, Jiayuh, Fuchs, James R., Ji, Min, Li, Ling, Xu, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905505/ https://www.ncbi.nlm.nih.gov/pubmed/26887043 http://dx.doi.org/10.18632/oncotarget.7336 |
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