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Inferring active regulatory networks from gene expression data using a combination of prior knowledge and enrichment analysis

BACKGROUND: Under both physiological and pathological conditions gene expression programs are shaped through the interplay of regulatory proteins and their gene targets, interactions between which form intricate gene regulatory networks (GRN). While the assessment of genome-wide expression for the c...

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Detalles Bibliográficos
Autores principales: Chouvardas, Panagiotis, Kollias, George, Nikolaou, Christoforos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905609/
https://www.ncbi.nlm.nih.gov/pubmed/27295045
http://dx.doi.org/10.1186/s12859-016-1040-7