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Inferring active regulatory networks from gene expression data using a combination of prior knowledge and enrichment analysis
BACKGROUND: Under both physiological and pathological conditions gene expression programs are shaped through the interplay of regulatory proteins and their gene targets, interactions between which form intricate gene regulatory networks (GRN). While the assessment of genome-wide expression for the c...
Autores principales: | Chouvardas, Panagiotis, Kollias, George, Nikolaou, Christoforos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905609/ https://www.ncbi.nlm.nih.gov/pubmed/27295045 http://dx.doi.org/10.1186/s12859-016-1040-7 |
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