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A comparative evaluation of data-merging and meta-analysis methods for reconstructing gene-gene interactions

BACKGROUND: We address the problem of integratively analyzing multiple gene expression, microarray datasets in order to reconstruct gene-gene interaction networks. Integrating multiple datasets is generally believed to provide increased statistical power and to lead to a better characterization of t...

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Detalles Bibliográficos
Autores principales: Lagani, Vincenzo, Karozou, Argyro D., Gomez-Cabrero, David, Silberberg, Gilad, Tsamardinos, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905611/
https://www.ncbi.nlm.nih.gov/pubmed/27294826
http://dx.doi.org/10.1186/s12859-016-1038-1