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Analysis tools for the interplay between genome layout and regulation

BACKGROUND: Genome layout and gene regulation appear to be interdependent. Understanding this interdependence is key to exploring the dynamic nature of chromosome conformation and to engineering functional genomes. Evidence for non-random genome layout, defined as the relative positioning of either...

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Detalles Bibliográficos
Autores principales: Bouyioukos, Costas, Elati, Mohamed, Képès, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905612/
https://www.ncbi.nlm.nih.gov/pubmed/27294345
http://dx.doi.org/10.1186/s12859-016-1047-0