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TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers

Lung cancer is the leading cause of cancer deaths worldwide; survival times are poor despite therapy. The role of the two-pore domain K(+) (K2P) channel TASK-1 (KCNK3) in lung cancer is at present unknown. We found that TASK-1 is expressed in non-small cell lung cancer (NSCLC) cell lines at variable...

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Detalles Bibliográficos
Autores principales: Leithner, Katharina, Hirschmugl, Birgit, Li, Yingji, Tang, Bi, Papp, Rita, Nagaraj, Chandran, Stacher, Elvira, Stiegler, Philipp, Lindenmann, Jörg, Olschewski, Andrea, Olschewski, Horst, Hrzenjak, Andelko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905626/
https://www.ncbi.nlm.nih.gov/pubmed/27294516
http://dx.doi.org/10.1371/journal.pone.0157453