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Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation

The Aryl hydrocarbon Receptor (AhR) is a transcription factor that mediates the biochemical response to xenobiotics and the toxic effects of a number of environmental contaminants, including dioxins. Recently, endogenous regulatory roles for the AhR in normal physiology and development have also bee...

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Detalles Bibliográficos
Autores principales: Corrada, Dario, Soshilov, Anatoly A., Denison, Michael S., Bonati, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905635/
https://www.ncbi.nlm.nih.gov/pubmed/27295348
http://dx.doi.org/10.1371/journal.pcbi.1004981