Addition of Everolimus Post VEGFR Inhibition Treatment Failure in Advanced Sarcoma Patients Who Previously Benefited from VEGFR Inhibition: A Case Series

BACKGROUND: Patients with metastatic sarcoma who progress on vascular endothelial growth factor receptor inhibitors (VEGFRi) have limited treatment options. Upregulation of the mTOR pathway has been demonstrated to be a means of resistance to targeted VEGFRi in metastatic sarcoma. PATIENTS AND METHO...

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Detalles Bibliográficos
Autores principales: ElNaggar, Adam C., Hays, John L., Chen, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905654/
https://www.ncbi.nlm.nih.gov/pubmed/27295141
http://dx.doi.org/10.1371/journal.pone.0156985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905654/
https://www.ncbi.nlm.nih.gov/pubmed/27295141
http://dx.doi.org/10.1371/journal.pone.0156985

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