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Discovery of Small-Molecule Modulators of the Human Y(4) Receptor

The human neuropeptide Y(4) receptor (Y(4)R) and its native ligand, pancreatic polypeptide, are critically involved in the regulation of human metabolism by signaling satiety and regulating food intake, as well as increasing energy expenditure. Thus, this receptor represents a putative target for tr...

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Detalles Bibliográficos
Autores principales: Sliwoski, Gregory, Schubert, Mario, Stichel, Jan, Weaver, David, Beck-Sickinger, Annette G., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905667/
https://www.ncbi.nlm.nih.gov/pubmed/27294784
http://dx.doi.org/10.1371/journal.pone.0157146