Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts

Cataracts are a significant public health problem with no proven methods for prevention. Discovery of novel disease mechanisms to delineate new therapeutic targets is of importance in cataract prevention and therapy. Herein, we report that mutations in the RagA GTPase (RRAGA), a key regulator of the...

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Detalles Bibliográficos
Autores principales: Chen, Jian-Huan, Huang, Chukai, Zhang, Bining, Yin, Shengjie, Liang, Jiajian, Xu, Ciyan, Huang, Yuqiang, Cen, Ling-Ping, Ng, Tsz-Kin, Zheng, Ce, Zhang, Shaobin, Chen, Haoyu, Pang, Chi-Pui, Zhang, Mingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905677/
https://www.ncbi.nlm.nih.gov/pubmed/27294265
http://dx.doi.org/10.1371/journal.pgen.1006090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905677/
https://www.ncbi.nlm.nih.gov/pubmed/27294265
http://dx.doi.org/10.1371/journal.pgen.1006090

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