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Ubiquitination independent of E1 and E2 enzymes by bacterial effectors
Signaling by ubiquitination regulates virtually every cellular process in eukaryotes. Covalent attachment of ubiquitin to a substrate is catalyzed by the E1, E2 and E3 three-enzyme cascade (1), which links the C terminus of ubiquitin via an isopeptide bond mostly to the ε-amino group of a lysine of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905768/ https://www.ncbi.nlm.nih.gov/pubmed/27049943 http://dx.doi.org/10.1038/nature17657 |