Cargando…

Ubiquitination independent of E1 and E2 enzymes by bacterial effectors

Signaling by ubiquitination regulates virtually every cellular process in eukaryotes. Covalent attachment of ubiquitin to a substrate is catalyzed by the E1, E2 and E3 three-enzyme cascade (1), which links the C terminus of ubiquitin via an isopeptide bond mostly to the ε-amino group of a lysine of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiu, Jiazhang, Sheedlo, Michael J., Yu, Kaiwen, Tan, Yunhao, Nakayasu, Ernesto S., Das, Chittaranjan, Liu, Xiaoyun, Luo, Zhao-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905768/ https://www.ncbi.nlm.nih.gov/pubmed/27049943 http://dx.doi.org/10.1038/nature17657

Ejemplares similares

A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination
por: Qiu, Jiazhang, et al.
Publicado: (2017)

Prediction of bacterial E3 ubiquitin ligase effectors using reduced amino acid peptide fingerprinting
por: McDermott, Jason E., et al.
Publicado: (2019)

Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes
por: Liu, Shuxin, et al.
Publicado: (2020)

The Legionella Effector SdjA Is a Bifunctional Enzyme That Distinctly Regulates Phosphoribosyl Ubiquitination
por: Song, Lei, et al.
Publicado: (2021)

Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase
por: Gan, Ninghai, et al.
Publicado: (2019)

A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin
por: Liu, Yao, et al.
Publicado: (2017)

Legionella longbeachae effector protein RavZ inhibits autophagy and regulates phagosome ubiquitination during infection
por: Shi, Yunjia, et al.
Publicado: (2023)

The mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector
por: Akturk, Anil, et al.
Publicado: (2018)

A Bifunctional Enzyme of Legionella that Distinctly Regulates Phosphoribosyl Ubiquitination of the SidE Family Effectors
por: Jiao, Jun, et al.
Publicado: (2022)

Hijacking of the Host Ubiquitin Network by Legionella pneumophila
por: Qiu, Jiazhang, et al.
Publicado: (2017)

Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination
por: Puvar, Kedar, et al.
Publicado: (2020)

The unity of opposites: Strategic interplay between bacterial effectors to regulate cellular homeostasis
por: Iyer, Shalini, et al.
Publicado: (2021)

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases
por: Pruneda, Jonathan N., et al.
Publicado: (2016)

Legionella pneumophila regulates host cell motility by targeting Phldb2 with a 14-3-3ζ-dependent protease effector
por: Song, Lei, et al.
Publicado: (2022)

Ubiquitin-Mimicking Peptides Transfer Differentiates by E1 and E2 Enzymes
por: Jin, Bo, et al.
Publicado: (2018)

Systematic Analysis of the Physiological Importance of Deubiquitinating Enzymes
por: Tsou, Wei-Ling, et al.
Publicado: (2012)

The NEL Family of Bacterial E3 Ubiquitin Ligases
por: Bullones-Bolaños, Andrea, et al.
Publicado: (2022)

Expression of ubiquitin-conjugating enzyme E2T in colorectal cancers and clinical implications
por: Wu, Xiangtian, et al.
Publicado: (2020)

Wheat germ-based protein libraries for the functional characterisation of the Arabidopsis E2 ubiquitin conjugating enzymes and the RING-type E3 ubiquitin ligase enzymes
por: Ramadan, Abdelaziz, et al.
Publicado: (2015)

Legionella pneumophila inhibits immune signaling via MavC-mediated transglutaminase-induced ubiquitination of UBE2N
por: Gan, Ninghai, et al.
Publicado: (2018)

Revisiting Bacterial Ubiquitin Ligase Effectors: Weapons for Host Exploitation
por: Pisano, Antonio, et al.
Publicado: (2018)

Protein ubiquitination and formation of polyubiquitin chains without ATP, E1 and E2 enzymes
por: Park, Sungjin, et al.
Publicado: (2015)

A Pathogen Type III Effector with a Novel E3 Ubiquitin Ligase Architecture
por: Singer, Alexander U., et al.
Publicado: (2013)

Ubiquitin-activating enzyme, E1, is associated with maturation of autophagic vacuoles
Publicado: (1992)

How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling
por: van der Heden van Noort, Gerbrand J., et al.
Publicado: (2018)

Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34
por: Williams, Katelyn M., et al.
Publicado: (2019)

Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12
por: Keyan, Kripa S, et al.
Publicado: (2023)

Secreted Bacterial Effectors That Inhibit Host Protein Synthesis Are Critical for Induction of the Innate Immune Response to Virulent Legionella pneumophila
por: Fontana, Mary F., et al.
Publicado: (2011)

The EHEC Type III Effector NleL Is an E3 Ubiquitin Ligase That Modulates Pedestal Formation
por: Piscatelli, Heather, et al.
Publicado: (2011)

Correction: A Pathogen Type III Effector with a Novel E3 Ubiquitin Ligase Architecture
por: Singer, Alexander U., et al.
Publicado: (2013)

Largazole and Its Derivatives Selectively Inhibit Ubiquitin Activating Enzyme (E1)
por: Ungermannova, Dana, et al.
Publicado: (2012)

E2 enzyme inhibition by stabilization of a low affinity interface with ubiquitin
por: Huang, Hao, et al.
Publicado: (2013)

E2 ubiquitin conjugating enzymes regulate the deubiquitinating activity of OTUB1
por: Wiener, Reuven, et al.
Publicado: (2013)

From seeds to trees: how E2 enzymes grow ubiquitin chains
por: Middleton, Adam J., et al.
Publicado: (2023)

Ubiquitin-Conjugating Enzyme E2 E Inhibits the Accumulation of Rice Stripe Virus in Laodelphax striatellus (Fallén)
por: Li, Yao, et al.
Publicado: (2020)

Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase
por: Spratt, Donald E., et al.
Publicado: (2012)

Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability
por: Shukla, Prakash K., et al.
Publicado: (2022)

The S. Typhi effector StoD is an E3/E4 ubiquitin ligase which binds K48- and K63-linked diubiquitin
por: McDowell, Melanie A, et al.
Publicado: (2019)

Bacterial Effector-Involved Temporal and Spatial Regulation by Hijack of the Host Ubiquitin Pathway
por: Kubori, Tomoko, et al.
Publicado: (2011)

Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors
por: Wang, Yong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_p55u09bqcqi9k3190mi7l70tss