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Tensin2-deficient mice on FVB/N background develop severe glomerular disease

Tensin2 (Tns2) is an essential component for the maintenance of glomerular basement membrane (GBM) structures. Tns2-deficient mice were previously shown to develop mild glomerular injury on a DBA/2 background, but not on a C57BL/6J or a 129/SvJ background, suggesting that glomerular injury by the de...

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Detalles Bibliográficos
Autores principales: UCHIO-YAMADA, Kozue, MONOBE, Yoko, AKAGI, Ken-ichi, YAMAMOTO, Yoshie, OGURA, Atsuo, MANABE, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905836/
https://www.ncbi.nlm.nih.gov/pubmed/26854109
http://dx.doi.org/10.1292/jvms.15-0442