(177)Lu-OPS201 targeting somatostatin receptors: in vivo biodistribution and dosimetry in a pig model

BACKGROUND: (177)Lu is used in peptide receptor radionuclide therapies for the treatment of neuroendocrine tumors. Based on the recent literature, SST2 antagonists are superior to agonists in tumor uptake. The compound OPS201 is the novel somatostatin antagonist showing the highest SST2 affinity. Th...

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Detalles Bibliográficos
Autores principales: Beykan, Seval, Dam, Jan S., Eberlein, Uta, Kaufmann, Jens, Kjærgaard, Benedict, Jødal, Lars, Bouterfa, Hakim, Bejot, Romain, Lassmann, Michael, Jensen, Svend Borup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906090/
https://www.ncbi.nlm.nih.gov/pubmed/27294582
http://dx.doi.org/10.1186/s13550-016-0204-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906090/
https://www.ncbi.nlm.nih.gov/pubmed/27294582
http://dx.doi.org/10.1186/s13550-016-0204-9

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