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The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway
Forms of Parkinson's disease (PD) are associated with lysosomal and autophagic dysfunction. ATP13A2, which is mutated in some types of early-onset Parkinsonism, has been suggested as a regulator of the autophagy–lysosome pathway. However, little is known about the ATP13A2 effectors and how they...
Autores principales: | Bento, Carla F., Ashkenazi, Avraham, Jimenez-Sanchez, Maria, Rubinsztein, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906231/ https://www.ncbi.nlm.nih.gov/pubmed/27278822 http://dx.doi.org/10.1038/ncomms11803 |
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