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Cryopreservation of human mesenchymal stromal cells expressing TRAIL for human anti-cancer therapy

BACKGROUND AIMS: Mesenchymal stromal cells (MSCs) are being extensively researched for cell therapy and tissue engineering. We have engineered MSCs to express the pro-apoptotic protein tumor necrosis factor–related apoptosis inducing ligand (TRAIL) and are currently preparing this genetically modifi...

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Detalles Bibliográficos
Autores principales: Yuan, Zhengqiang, Lourenco, Sofia Da Silva, Sage, Elizabeth K., Kolluri, Krishna K., Lowdell, Mark W., Janes, Sam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906234/
https://www.ncbi.nlm.nih.gov/pubmed/27260207
http://dx.doi.org/10.1016/j.jcyt.2016.04.005