Cargando…

Stimulation of Synaptic Vesicle Exocytosis by the Mental Disease Gene DISC1 is Mediated by N-Type Voltage-Gated Calcium Channels

Lesions and mutations of the DISC1 (Disrupted-in-schizophrenia-1) gene have been linked to major depression, schizophrenia, bipolar disorder and autism, but the influence of DISC1 on synaptic transmission remains poorly understood. Using two independent genetic approaches—RNAi and a DISC1 KO mouse—w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Willcyn, Thevathasan, Jervis Vermal, Lin, Qingshu, Lim, Kim Buay, Kuroda, Keisuke, Kaibuchi, Kozo, Bilger, Marcel, Soong, Tuck Wah, Fivaz, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906242/ https://www.ncbi.nlm.nih.gov/pubmed/27378904 http://dx.doi.org/10.3389/fnsyn.2016.00015

Ejemplares similares

The small GTPase HRas shapes local PI3K signals through positive feedback and regulates persistent membrane extension in migrating fibroblasts
por: Thevathasan, Jervis Vermal, et al.
Publicado: (2013)

STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs
por: Garcia-Alvarez, Gisela, et al.
Publicado: (2015)

β subunits of voltage-gated calcium channels in cardiovascular diseases
por: Loh, Kelvin Wei Zhern, et al.
Publicado: (2023)

Bidirectional modulation of hippocampal synaptic plasticity by Dopaminergic D4-receptors in the CA1 area of hippocampus
por: Navakkode, Sheeja, et al.
Publicado: (2017)

BARP suppresses voltage-gated calcium channel activity and Ca(2+)-evoked exocytosis
por: Béguin, Pascal, et al.
Publicado: (2014)

How voltage-gated calcium channels gate forms of homeostatic synaptic plasticity
por: Frank, C. Andrew
Publicado: (2014)

Sensing Exocytosis and Triggering Endocytosis at Synapses: Synaptic Vesicle Exocytosis–Endocytosis Coupling
por: Lou, Xuelin
Publicado: (2018)

Synaptic and voltage-gated currents in interplexiform cells of the tiger salamander retina
Publicado: (1990)

Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells
por: Salunkhe, V A, et al.
Publicado: (2015)

Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics
por: Park, Sung Jin, et al.
Publicado: (2015)

L‐type Voltage‐Gated calcium channels partly mediate Mechanotransduction in the intervertebral disc
por: Poillot, Philip, et al.
Publicado: (2022)

Morphofunctional changes at the active zone during synaptic vesicle exocytosis
por: Radecke, Julika, et al.
Publicado: (2023)

Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis
por: Ogunmowo, Tyler H., et al.
Publicado: (2023)

Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis
por: Ho, Wan Yun, et al.
Publicado: (2020)

Epigenetic regulation of microglial phosphatidylinositol 3‐kinase pathway involved in long‐term potentiation and synaptic plasticity in rats
por: Saw, Genevieve, et al.
Publicado: (2019)

Coupling between Voltage Sensors and Activation Gate in Voltage-gated K(+) Channels
por: Lu, Zhe, et al.
Publicado: (2002)

Sphingosine Facilitates SNARE Complex Assembly and Activates Synaptic Vesicle Exocytosis
por: Darios, Frédéric, et al.
Publicado: (2009)

RIM1α SUMOylation Is Required for Fast Synaptic Vesicle Exocytosis
por: Girach, Fatima, et al.
Publicado: (2013)

Kiss-and-Run Is a Significant Contributor to Synaptic Exocytosis and Endocytosis in Photoreceptors
por: Wen, Xiangyi, et al.
Publicado: (2017)

Epileptic Phenotypes Associated With SNAREs and Related Synaptic Vesicle Exocytosis Machinery
por: Cali, Elisa, et al.
Publicado: (2022)

straightjacket is required for the synaptic stabilization of cacophony, a voltage-gated calcium channel α(1) subunit
por: Ly, Cindy V., et al.
Publicado: (2008)

Hysteresis in voltage-gated channels
por: Villalba-Galea, Carlos A.
Publicado: (2016)

Rho-Kinase/ROCK Phosphorylates PSD-93 Downstream of NMDARs to Orchestrate Synaptic Plasticity
por: Hossen, Emran, et al.
Publicado: (2022)

Voltage-gated sodium channels assemble and gate as dimers
por: Clatot, Jérôme, et al.
Publicado: (2017)

Structural dynamics determine voltage and pH gating in human voltage-gated proton channel
por: Han, Shuo, et al.
Publicado: (2022)

Understanding alternative splicing of Ca(v)1.2 calcium channels for a new approach towards individualized medicine
por: Liao, Ping, et al.
Publicado: (2010)

Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis
por: Leal-Ortiz, Sergio, et al.
Publicado: (2008)

Structural transitions in the synaptic SNARE complex during Ca(2+)-triggered exocytosis
por: Han, Xue, et al.
Publicado: (2006)

Neurotransmitter Secretion along Growing Nerve Processes: Comparison with Synaptic Vesicle Exocytosis
por: Zakharenko, Stanislav, et al.
Publicado: (1999)

Botulinum Neurotoxin a Blocks Synaptic Vesicle Exocytosis but Not Endocytosis at the Nerve Terminal
por: Neale, Elaine A., et al.
Publicado: (1999)

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release
Publicado: (1979)

Regulated Exocytosis of GABA-containing Synaptic-like Microvesicles in Pancreatic β-cells
por: Braun, Matthias, et al.
Publicado: (2004)

Inhibitors of synaptic vesicle exocytosis reduce surface expression of postsynaptic glutamate receptors
por: Woo, Dong Ho, et al.
Publicado: (2020)

Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice
por: Bin Saifullah, Md. Ali, et al.
Publicado: (2018)

Molecular mechanism of voltage sensing in voltage-gated proton channels
por: Gonzalez, Carlos, et al.
Publicado: (2013)

Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP
por: Shen, Rong, et al.
Publicado: (2022)

Caution Is Required in Interpretation of Mutations in the Voltage Sensing Domain of Voltage Gated Channels as Evidence for Gating Mechanisms
por: Kariev, Alisher M., et al.
Publicado: (2015)

Lipid-dependent gating of a voltage-gated potassium channel
por: Zheng, Hui, et al.
Publicado: (2011)

The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation
por: Cosentino, Katia, et al.
Publicado: (2022)

N-type voltage gated calcium channels mediate excitatory synaptic transmission in the anterior cingulate cortex of adult mice
por: Kang, SukJae Joshua, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_a3k8rimg8p9vgjppt7e2r2mgma