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Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

The regulation of many protein kinases by binding to calcium/calmodulin connects two principal mechanisms in signaling processes: protein phosphorylation and responses to dose- and time-dependent calcium signals. We used the calcium/calmodulin-dependent members of the death-associated protein kinase...

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Detalles Bibliográficos
Autores principales: Simon, Bertrand, Huart, Anne-Sophie, Temmerman, Koen, Vahokoski, Juha, Mertens, Haydyn D.T., Komadina, Dana, Hoffmann, Jan-Erik, Yumerefendi, Hayretin, Svergun, Dmitri I., Kursula, Petri, Schultz, Carsten, McCarthy, Andrew A., Hart, Darren J., Wilmanns, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906247/
https://www.ncbi.nlm.nih.gov/pubmed/27133022
http://dx.doi.org/10.1016/j.str.2016.03.020