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Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport

Membrane contact sites between the ER and multivesicular endosomes/bodies (MVBs) play important roles in endosome positioning and fission and in neurite outgrowth. ER-MVB contacts additionally function in epidermal growth factor receptor (EGFR) tyrosine kinase downregulation by providing sites where...

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Detalles Bibliográficos
Autores principales: Eden, Emily R., Sanchez-Heras, Elena, Tsapara, Anna, Sobota, Andrzej, Levine, Tim P., Futter, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906250/
https://www.ncbi.nlm.nih.gov/pubmed/27270042
http://dx.doi.org/10.1016/j.devcel.2016.05.005